A strange question, but one that merits an answer indeed.
Being happy is a relative state of emotion; if we take a person from an impoverished country living in slum and gutter, and move them to one of our country's placing them in a home in a ghetto, they will be ecstatic. Why? because they have moved to a better state of being even though to us a ghetto isn't exactly a palatial environment. Similarly if one moves from a path that they feel restricted in, and move to one that offers more freedom of spirit, again they will be happy because the relative situation has been made better for them.
I feel that finding a way to better ones situation, without bringing harm to anyone else, is perfectly valid given any opportunity, I see nothing wrong with that. Being happy puts us in a better frame of mind, makes us more socially approachable, improves our work ethic and many other things besides. So yes, I believe humans are supposed to be happy, or at least content.